abstract：BACKGROUND:Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to evaluate perioperative management using new inhalant drugs in patients with obs...

journal_title：BMC pulmonary medicine

authors： Numata T,Nakayama K,Fujii S,Yumino Y,Saito N,Yoshida M,Kurita Y,Kobayashi K,Ito S,Utsumi H,Yanagisawa H,Hashimoto M,Wakui H,Minagawa S,Ishikawa T,Hara H,Araya J,Kaneko Y,Kuwano K

更新日期：2018-01-09 00:00:00

abstract：BACKGROUND:Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe hypersensitivity drug reaction involving the skin and multiple internal organ systems. The symptoms typically present with fever and skin rash, and rapidly progress to multiple organ failures. Vancomycin is a rare drug to cause DRESS s...

journal_title：BMC pulmonary medicine

authors： Wilcox O,Hassanein M,Armstrong J,Kassis N

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:Pneumonia poses a significant burden to the U.S. health-care system. However, there are few data focusing on severe pneumonia, particularly cases of pneumonia associated with specialized care in intensive care units (ICU). METHODS:We used administrative and electronic medical record data from six integrated...

journal_title：BMC pulmonary medicine

authors： Storms AD,Chen J,Jackson LA,Nordin JD,Naleway AL,Glanz JM,Jacobsen SJ,Weintraub ES,Klein NP,Gargiullo PM,Fry AM

更新日期：2017-12-16 00:00:00

abstract：BACKGROUND:In bronchiectasis patients, chronic Pseudomonas aeruginosa (PA) infection has been associated with worse health-related quality of life (HRQL), but little is known about Mycobacterium avium complex lung disease (MACLD) patients in this context. This study aimed to evaluate HRQL and investigate the impact of ...

journal_title：BMC pulmonary medicine

authors： Kamata H,Asakura T,Suzuki S,Namkoong H,Yagi K,Funatsu Y,Okamori S,Uno S,Uwamino Y,Fujiwara H,Nishimura T,Ishii M,Betsuyaku T,Hasegawa N

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate. METHODS:In this study, we searched the PubMed, EmBase, and Coch...

journal_title：BMC pulmonary medicine

authors： Zhang HL,Tan M,Qiu AM,Tao Z,Wang CH

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machinery and epithelial barrier integrity genes. We used a targeted gene expression arrays to identify cha...

journal_title：BMC pulmonary medicine

authors： Pascoe CD,Obeidat M,Arsenault BA,Nie Y,Warner S,Stefanowicz D,Wadsworth SJ,Hirota JA,Jasemine Yang S,Dorscheid DR,Carlsten C,Hackett TL,Seow CY,Paré PD

更新日期：2017-12-11 00:00:00

abstract：BACKGROUND:Despite the recent increasing worldwide attention towards pulmonary hypertension (PH), its epidemiology remains poorly described in Africa. Accordingly, we performed a systematic review and meta-analysis of PH prevalence, incidence and etiologies in Africa. METHODS:We searched PubMed, EMBASE, African Journa...

journal_title：BMC pulmonary medicine

authors： Bigna JJ,Noubiap JJ,Nansseu JR,Aminde LN

更新日期：2017-12-08 00:00:00

abstract：BACKGROUND:Although pleural fluid lactate dehydrogenase (LDH) and adenosine deaminase (ADA) levels are often used to distinguish between tuberculous pleural effusion (TPE) and parapneumonic pleural effusion (PPE), this can be challenging as the LDH level may vary from normal to severely increased in PPE and a significa...

journal_title：BMC pulmonary medicine

authors： Wang J,Liu J,Xie X,Shen P,He J,Zeng Y

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Subcutaneous treprostinil is a prostacyclin analogue used to treat pulmonary arterial hypertension (PAH). Due to local pain it can cause a deterioration of heart related quality of life (HRQoL) or even abandonment of treatment. The aim of this paper was to assess the feasibility of treatment with intravenous...

journal_title：BMC pulmonary medicine

authors： Kurzyna M,Małaczyńska-Rajpold K,Koteja A,Pawlak A,Chrzanowski Ł,Furdal M,Gąsior Z,Jacheć W,Sobkowicz B,Norwa J,Mularek-Kubzdela T,Torbicki A

更新日期：2017-12-02 00:00:00

abstract：BACKGROUND:The long-term prognosis of chronic cough and its determinants need to be clarified. METHODS:This is a prospective, observational cohort study. Eighty-nine unselected subjects with chronic (> 8 weeks' duration) cough were carefully investigated: Clinical examination, symptom questionnaire, Leicester Cough Qu...

journal_title：BMC pulmonary medicine

authors： Koskela HO,Lätti AM,Purokivi MK

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Combined effects of leaks, mechanical property of respiratory system and upper airway (UA) patency on patient-ventilator synchrony (PVA) and the level of clinically "tolerable" leaks are not well established in home ventilators. METHODS:We comparatively assessed on a bench model, the highest leak level tole...

journal_title：BMC pulmonary medicine

authors： Zhu K,Rabec C,Gonzalez-Bermejo J,Hardy S,Aouf S,Escourrou P,Roisman G

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Clinical guidelines specify that diagnosis of interstitial pulmonary fibrosis (IPF) requires identification of usual interstitial pneumonia (UIP) pattern. While UIP can be identified by high resolution CT of the chest, the results are often inconclusive, making surgical lung biopsy necessary to reach a defin...

journal_title：BMC pulmonary medicine

authors： Choi Y,Lu J,Hu Z,Pankratz DG,Jiang H,Cao M,Marchisano C,Huiras J,Fedorowicz G,Wong MG,Anderson JR,Tom EY,Babiarz J,Imtiaz U,Barth NM,Walsh PS,Kennedy GC,Huang J

更新日期：2017-11-17 00:00:00

abstract：BACKGROUND:Idiopathic Pulmonary Fibrosis (IPF) is a fatal fibrotic lung disease occurring predominantly in middle-aged and older adults. The traditional diagnostic classification of IPF is based on clinical, radiological, and histopathological features. However, the considerable heterogeneity in IPF presentation sugges...

journal_title：BMC pulmonary medicine

authors： Wang Y,Yella J,Chen J,McCormack FX,Madala SK,Jegga AG

更新日期：2017-10-20 00:00:00

abstract：BACKGROUND:Late-onset noninfectious pulmonary complications (LONIPCs), which occur more than 3 months after allogeneic hematopoietic stem cell transplantation (HSCT), are major causes of morbidity and mortality after transplantation. Among LONIPCs, we occasionally treat patients with late-onset severe restrictive lung ...

journal_title：BMC pulmonary medicine

authors： Namkoong H,Ishii M,Mori T,Sugiura H,Tasaka S,Sakurai M,Koda Y,Kato J,Hasegawa N,Okamoto S,Betsuyaku T

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:The lung-protective ventilation bundle has been shown to reduce mortality in adult acute respiratory distress syndrome (ARDS). This concept has expanded to other areas of acute adult ventilation and is recommended for pediatric ventilation. A component of lung-protective ventilation relies on a prediction of...

journal_title：BMC pulmonary medicine

authors： Martin DC,Richards GN

更新日期：2017-05-23 00:00:00

abstract：BACKGROUND:Influenza is a frequent cause of exacerbations of chronic obstructive pulmonary disease (COPD). Exacerbations are associated with worsening of the airflow obstruction, hospitalisation, reduced quality of life, disease progression, death, and ultimately, substantial healthcare-related costs. Despite longstand...

journal_title：BMC pulmonary medicine

authors： Bekkat-Berkani R,Wilkinson T,Buchy P,Dos Santos G,Stefanidis D,Devaster JM,Meyer N

更新日期：2017-05-03 00:00:00

abstract：BACKGROUND:The FACED score is an easy-to-use multidimensional grading system that has demonstrated an excellent prognostic value for mortality in patients with bronchiectasis. A Spanish group developed the score but no multicenter international validation has yet been published. METHODS:Retrospective and multicenter s...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Pereira MC,Gramblicka G,Cavalcanti-Lundgren F,de Figueiredo MF,Arancibia F,Rached S,de la Rosa D,Máiz-Carro L,Girón R,Olveira C,Prados C,Martinez-Garcia MA

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Electromagnetic navigation bronchoscopy (ENB) is an image-guided, minimally invasive approach that uses a flexible catheter to access pulmonary lesions. METHODS:NAVIGATE is a prospective, multicenter study of the superDimension™ navigation system. A prespecified 1-month interim analysis of the first 1,000 p...

journal_title：BMC pulmonary medicine

authors： Khandhar SJ,Bowling MR,Flandes J,Gildea TR,Hood KL,Krimsky WS,Minnich DJ,Murgu SD,Pritchett M,Toloza EM,Wahidi MM,Wolvers JJ,Folch EE,NAVIGATE Study Investigators.

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Although the prevalence of both obstructive sleep apnoea (OSA) and asthma are both increasing, little is known about the impact of OSA on the natural history of lung function in asthmatic patients. METHODS:A total of 466 patients from our sleep laboratory were retrospectively enrolled. Of them, 77 patients ...

journal_title：BMC pulmonary medicine

authors： Wang TY,Lo YL,Lin SM,Huang CD,Chung FT,Lin HC,Wang CH,Kuo HP

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness ...

journal_title：BMC pulmonary medicine

authors： Schultz K,Seidl H,Jelusic D,Wagner R,Wittmann M,Faller H,Nowak D,Schuler M

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:The Birt-Hogg-Dubé (BHD) syndrome is a very rare autosomal dominant form of genodermatosis caused by germline mutations in the folliculin (FLCN) gene, which is mapped to the p11.2 region in chromosome 17. BHD commonly presents cutaneous fibrofolliculomas, pulmonary cysts, renal cell carcinoma, and recurrent ...

journal_title：BMC pulmonary medicine

authors： Hao S,Long F,Sun F,Liu T,Li D,Jiang S

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:Innate T helper type 2 (Th2) immune responses mediated by interleukin (IL)-33, thymic stromal lymphopoietin (TSLP), and IL-25 have been shown to play an important role in pulmonary fibrosis of animal models; however, their clinical implications remain poorly understood. METHODS:TSLP, IL-25, and IL-33 concen...

journal_title：BMC pulmonary medicine

authors： Lee JU,Chang HS,Lee HJ,Jung CA,Bae DJ,Song HJ,Park JS,Uh ST,Kim YH,Seo KH,Park CS

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Hyperoxia is common early in the course of resuscitation of critically ill patients. It has been associated with mortality in some, but not all, studies of cardiac arrest patients and other critically ill cohorts. Reasons for the inconsistency are unclear and may depend on unmeasured patient confounders, the...

journal_title：BMC pulmonary medicine

authors： Russell DW,Janz DR,Emerson WL,May AK,Bernard GR,Zhao Z,Koyama T,Ware LB

更新日期：2017-02-03 00:00:00

abstract：BACKGROUND:To investigate if age, gender and smoking are associated with airway wall thickness (AWT) measured by high resolution computed tomography (HRCT) and if higher AWT is associated with lower levels of pulmonary function in healthy current- and never-smokers with a wide age range. METHODS:HRCT scans were perfor...

journal_title：BMC pulmonary medicine

authors： Telenga ED,Oudkerk M,van Ooijen PM,Vliegenthart R,Ten Hacken NH,Postma DS,van den Berge M

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) have increased cardiovascular risk. Natriuretic peptides (NP) in other populations are useful in identifying cardiovascular disease, stratifying risk, and guiding therapy. METHODS:We performed a systematic literature review to examine NP in COPD, ut...

journal_title：BMC pulmonary medicine

authors： Hawkins NM,Khosla A,Virani SA,McMurray JJ,FitzGerald JM

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Physical and psychological symptoms are the hallmark of patients' subjective perception of their illness. The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation. METHODS...

journal_title：BMC pulmonary medicine

authors： Nguyen HQ,Herting JR,Pike KC,Gharib SA,Matute-Bello G,Borson S,Kohen R,Adams SG,Fan VS

更新日期：2016-12-03 00:00:00

abstract：BACKGROUND:Hypoxemia is a major complication of COPD and is a strong predictor of mortality. We previously identified independent risk factors for the presence of resting hypoxemia in the COPDGene cohort. However, little is known about characteristics that predict onset of resting hypoxemia in patients who are normoxic...

journal_title：BMC pulmonary medicine

authors： Wells JM,Estepar RS,McDonald MN,Bhatt SP,Diaz AA,Bailey WC,Jacobson FL,Dransfield MT,Washko GR,Make BJ,Casaburi R,van Beek EJ,Hoffman EA,Sciurba FC,Crapo JD,Silverman EK,Hersh CP,COPDGene Investigators.

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:During the last few years, investigators have debated the role that infectious agents may have in sarcoidosis pathogenesis. With the emergence of new molecular biology techniques, several studies have been conducted; therefore, we performed a meta-analysis in order to better explain this possible association...

journal_title：BMC pulmonary medicine

authors： Esteves T,Aparicio G,Garcia-Patos V

更新日期：2016-11-28 00:00:00

abstract：BACKGROUND:The incidence and prevalence of chronic kidney disease (CKD) continue to rise worldwide. Increasing age, diabetes, hypertension, and cigarette smoking are well-recognized risk factors for CKD. Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation leading to airway obstr...

journal_title：BMC pulmonary medicine

authors： Gaddam S,Gunukula SK,Lohr JW,Arora P

更新日期：2016-11-24 00:00:00

abstract：BACKGROUND:Despite advances in asthma treatment, severe asthma (SA) still results in high morbidity and use of health resources. Our hypothesis was that SA patients would achieve adequate control with a systematic protocol, including oral corticosteroids, budesonide/formoterol maintenance and reliever therapy and a mul...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Carvalho-Pinto R,Fernandes FL,Rached S,Rabe K,Cukier A,Stelmach R

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:Programmed cell death 5 (PDCD5) was first identified as an apoptosis-promoting protein and involved in some autoimmune diseases and inflammatory processes. Our previous study demonstrated greater expression of serum PDCD5 in asthmatic patients than controls. This study aimed to further explore the significan...

journal_title：BMC pulmonary medicine

authors： Diao X,Wang J,Zhu H,He B

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD. METHODS:E...

journal_title：BMC pulmonary medicine

authors： Matsson H,Söderhäll C,Einarsdottir E,Lamontagne M,Gudmundsson S,Backman H,Lindberg A,Rönmark E,Kere J,Sin D,Postma DS,Bossé Y,Lundbäck B,Klar J

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:Abediterol is a novel, once-daily long-acting β2-agonist in development for the treatment of chronic obstructive pulmonary disease (COPD) and asthma in combination with an anti-inflammatory agent. This Phase IIa, randomised, double-blind, crossover study investigated the bronchodilation, safety, tolerability...

journal_title：BMC pulmonary medicine

authors： Beier J,Pujol H,Seoane B,Jimenez E,Astbury C,Massana E,Ruiz S,de Miquel G

更新日期：2016-07-20 00:00:00

abstract：BACKGROUND:The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. Our aim was to compare real life operational characteristics for three EGFR mutation assays - two targeted approaches ...

journal_title：BMC pulmonary medicine

authors： Cernomaz AT,Macovei II,Pavel I,Grigoriu C,Marinca M,Baty F,Peter S,Zonda R,Brutsche M,Grigoriu B

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:People with cystic fibrosis (CF) may work in healthcare settings risking nosocomial pathogen acquisition. The aim of this study was to determine the incidence of methicillin-resistant Staphylococcus aureus (MRSA) infection in adult healthcare workers with CF (HCWcf). METHODS:Data was collected in this obser...

journal_title：BMC pulmonary medicine

authors： Wood ME,Sherrard LJ,Ramsay KA,Yerkovich ST,Reid DW,Kidd TJ,Bell SC

更新日期：2016-05-11 00:00:00

abstract：BACKGROUND:Although the heterogeneous nature of asthma has prompted asthma phenotyping with physiological or biomarker data, these studies have been mostly cross-sectional. Longitudinal studies that assess the stability of phenotypes based on a combination of physiological, clinical and biomarker data are currently lac...

journal_title：BMC pulmonary medicine

authors： Zaihra T,Walsh CJ,Ahmed S,Fugère C,Hamid QA,Olivenstein R,Martin JG,Benedetti A

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:Endotoxin from Gram-negative bacteria are found in different concentrations in dust and on the ground of laboratories dealing with small animals and animal houses. METHODS:Cross-sectional study performed in workplaces of two universities. Dust samples were collected from laboratories and animal facilities h...

journal_title：BMC pulmonary medicine

authors： Freitas AS,Simoneti CS,Ferraz E,Bagatin E,Brandão IT,Silva CL,Borges MC,Vianna EO

更新日期：2016-05-06 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a form of chronic fibrosing interstitial pneumonia characterized by progressive worsening of dyspnea and lung function, with a poor prognosis. The objective of this study was to determine treatment patterns, resource use and costs of managing Spanish patients with IPF. ...

journal_title：BMC pulmonary medicine

authors： Morell F,Esser D,Lim J,Stowasser S,Villacampa A,Nieves D,Brosa M

更新日期：2016-01-12 00:00:00

abstract：BACKGROUND:YKL-40 is an extracellular matrix glycoprotein with a significant role in tissue inflammation and remodeling. MIP-1a has chemotactic and pro-inflammatory properties, and is induced by YKL-40 in several lung disorders. The aim of this study was to determine the levels of YKL-40 and MIP-1a in blood serum and p...

journal_title：BMC pulmonary medicine

authors： Adamidi T,Soulitzis N,Neofytou E,Zannetos S,Georgiou A,Benidis K,Papadopoulos A,Siafakas NM,Schiza SE

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Noninvasive ventilation (NIV) is used in critically ill patients with acute respiratory failure (ARF) to avoid endotracheal intubation. However, the impact of NIV use on ARF patient's outcomes is still unclear. Our objectives were to evaluate the rate of NIV failure in hypoxemic patients with an arterial car...

journal_title：BMC pulmonary medicine

authors： Corrêa TD,Sanches PR,de Morais LC,Scarin FC,Silva E,Barbas CS

更新日期：2015-11-11 00:00:00